ALDEIDOS E CETONAS PDF

ALDEIDOS E CETONAS PDF

Veja grátis o arquivo Aldeidos e cetonas (1) enviado para a disciplina de Química Orgânica II Categoria: Outros – Veja grátis o arquivo aldeidos e cetonas enviado para a disciplina de Química Orgânica Categoria: Aulas – Veja grátis o arquivo a aldeídos e cetonas QUI 4 enviado para a disciplina de Química Orgânica II Categoria: Aulas – 4 –

Author: Faunos JoJolmaran
Country: Mexico
Language: English (Spanish)
Genre: Automotive
Published (Last): 9 February 2017
Pages: 262
PDF File Size: 9.46 Mb
ePub File Size: 20.51 Mb
ISBN: 472-1-54430-232-8
Downloads: 85461
Price: Free* [*Free Regsitration Required]
Uploader: Mikalar

Enviado por Karine flag Denunciar. Acetal formation from ketones and simple alcohols is less favorable than formation from aldehydes.

But there is a problem! Now the compound will dissolve in water and release dapsone inside the patient. Each inserting fetonas requires two atoms of lithium and generates one equivalent of lithium halide salt.

The mechanism of the reaction is not completely understood but a possible but probably not very accurate way of writing the mechanism is shown here: Overall it involves an insertion of magnesium into the new carbon—halogen bond.

You may ask how this is possible since dap- sone has no aldehyde or ketone—just two amino groups and a sulfone. Iodides, bromides, and chlorides can be used, as can both aryl and alkyl halides, though they cannot contain any functional groups that would react with the Grignard reagent once it is formed. In this book we shall not be concerned with these details, and it will suffice always to represent organometallic compounds as simple monomeric structures.

Thioacetals can be converted to CH2 groups by hydrogenation using a catalyst such as Raney nickel.

The second reason that bisulfite compounds are useful is that they are soluble in water. But it can matter to medicinal chemists, who make compounds that need to be com- patible with biological systems.

  CINEMATIQUE DU SOLIDE INDEFORMABLE PDF

Acetal formation is reversible An excess of water in the presence of an acid catalyst will hydrolyze an acetal to. Dissolving aldehydes or ketones in water causes formation of an equilibrium between the carbonyl compound and its hydrate. Mild acid facilitates departure of the hydroxyl group from the aminoalcohol intermediate without ceonas protonating the cetonax of the amine starting co mpound.

How to make organolithium reagents Organolithium compounds may be made by a similar oxidative insertion reaction from lithium metal and alkyl halides. The ether solvent is essential for Grignard formation because 1 ethers unlike, say, alcohols or dichloromethane will not react with Grignards and, more impor- tantly, 2 only in ethers are Grignard reagents soluble.

In Chapter 5 you saw how triethylamine forms a complex with the Lewis acid BF3, and much the same happens when an ether meets a metal ion such as magnesium or lithium: But most larger more than four or so carbon atoms aldehydes and ketones are not. Aldehydes and ketones react with phosphorous ylides to produce alkenes An ylide is a neutral molecule with adjacent positive and negative charges. Aldehydes and ketones react with primary amines and ammonia to yield imines They react with secondary amines to yield enamines.

An aldehyde or ketone in the presence of excess alcohol and an acid catalyst will form an acetal. The bisulfite compound of formaldehyde CH2O has special significance. Organometallics as bases Organometallics need to be kept absolutely free of moisture—even moisture in the air will destroy them.

Aldeídos e cetonas

Initiation can be accomplished by adding a small amount. The reaction is therefore known as an oxidative insertion or oxidative addition, and is a general process for many metals such as Mg, Li which we meet shortlyCu, and Zn. The true structure of organolithiums and Grignard reagents is rather more complicated!

  DHAMMAPADA SINHALA PDF

Initiation can be accomplished by adding a small amount of iodine or 1,2-diiodoethane, or by using ultra- sound to dislodge the oxide layer. The details of this sort of chemistry will come in Chapter 14 when you will meet imines as intermediates. The compound is commercially available and, together with the related zinc salt, is widely used in the textile industry as a reduc- ing agent.

Secondary amines cannot form a neutral imine by loss of a second proton on nitrogen An enamine is formed instead.

aldeidos e cetonas

An aldehyde or ketone dissolved in an alcohol will form an equilibrium mixture containing the corresponding hemiacetal. Here are some examples. The tetrahedral carbon resulting from addition to an aldehyde is alddidos sterically hindered than the tetrahedral carbon resulting from addition to a ketone.

Acylic hemiacetals are generally not stable, however, cyclic five-and sixmembered ring hemiacetals are. Some people like eating these, but it is cetonnas to eat too many at one sitting! Formation of the acetal proceeds via the corresponding hemiacetal An acetal has two alkoxyl groups bonded to the same carbon.